The relevance. Under operating conditions gas pipelines work at a time variable pressure level (in general, at a random level with unknown distribution law) and change (random variation relative to the annual trend) of ambient temperature. Due to the mentioned conditions, the stresses occurring in pipe walls are not described by the laws proposed and studied in the framework of the theory of parametric statistics. The basis for predicting a gas pipeline life is the pipe material fatigue curve connecting the amplitude of the actual stresses with the number of cycles of the tested sample deformations rather but not with the time of their operation until they are destroyed. In order to determine a gas pipeline residual service life in operation in the course of time, it is necessary to estimate a fatigue damage accumulation in its material under any law of stress distribution, regardless of its complexity. Currently, there are no methods for predicting gas pipeline residual service life, taking into account the actual range of changes in external loads and the processes of fatigue damage accumulation in pipe walls. Since gas pipelines are potentially dangerous objects, the determination of their residual life by the operation time is the most important task. The main aim of the study is to determine gas pipeline residual service life in a time span with the given non-destruction probability, when the pipeline is exposed to a random range of external loads during its operation, regardless of the range complexity, taking into account the processes of fatigue damage accumulation in the pipeline. Methods: the kinetic theory of mechanical fatigue, methods of nonparametric statistics, measurement of cyclic deformations using variable sensitivity integral strain gauges. Results. The authors have developed a computational and experimental method based on integrated use of the kinetic theory of mechanical fatigue, taking into account damage accumulation in cyclic deformation of products, methods of nonparametric statistics, providing restoration of function of stress distribution density regardless of the complexity of the law of their changes during pipeline operation and original means of measuring cyclic deformations – variable sensitivity integral strain gauges. The main stages of the method implementation was considered. The authors obtained the mathematical relations for determining the number of loading cycles, equivalent by damaging effect, to restore the duration of the stages of the stresses aggregate and to calculate the stresses, equivalent by damaging effect, according to the recorded by the gauge value of displacement of its response limits (the first «dark spots») during the gas pipeline operation based on the equations developed in the framework of the kinetic theory of fatigue. On the example of the method implementation, a relationship of gas pipeline residual life defined by the gauge response was established, which allows estimating quickly the residual service life of various sections of a gas pipeline under operating conditions. The paper demonstrates an alternative use of the method results to determine the effect of different amounts of gas pipeline corrosion defects on its residual service life.