The relevance of the research is caused by the lack of study of relations between relief and construction of gas transportation systems. The decision of scientific and applied engineering problems, such as choice of optimal route for pipelines, design of measures for engineering protection of facilities and land reclamation, planning of monitoring areas of gas transportation systems, requires an assessment of engineering and geomorphological conditions. This study represents regional-scaled experience of such an assessment. The aim of this work is the regional engineering geomorphological assessment of the area of gas transportation systems passage (for example, the site of the proposed gas pipeline in the Saratov region). The assessment was carried out by morphometric, morpholithologic, morphodynamic and complex criteria applicable at the regional scale level. Methods: cartographic method, comparative-geographical method, field geomorphological and landscape mapping, morphometric and statistical analysis, morpholithogenesis analysis, GIS analysis (using radar digital topographic database SRTM), interpretation of space images. Graphics and design build was performed by using MS Office, ArcGIS, AutoCAD and Global Mapper. Results. The author has carried out regional engineering assessment of the relief for the route of gas transportation systems in Saratov region. At the site selected for regional assessment, the most difficult geomorphological areas are presented at the crossings of river valleys. The slopes and bottoms of the valleys, alternating with the watershed areas, determine the route differentiation by morpholithological and morphodynamic conditions. The Northern part of the territory is more favorable in terms of the terrain dissection along the route. At the same time, in the South (in the Lysogorsky district) there is more developed transport infrastructure.