The relevance of the issue is caused by the need to study the rounded micro-grains (globules, spherules) of pseudorutile accessories found in Aleysko-Zmeinogorsk granitoid complex (D2-3). The aim of the study is to study in details occurrence and chemical composition of pseudorutile globules in granitoids being subsequent alumnia-silicate melt differentiates, paragenetic associations, pseudorutile globule formations as altered product of primary ore-for-ming elements - titanium and ferrum. The research methods. Mineralogical samples of 5...7 kg were extracted from both granitoid outcroppings and quarries. Analytical analysis was carried out on electron scanning microscope (ESM) JSM-6510LV (Jeol Ltd) and energy-dispersive spectrometer INCA Energy 350+ in the Laboratory of X-ray Spectrum Analysis, Institute of Geology and Mineralogy, Siberian Branch, RAS (Novosibirsk). The results. The paper introduces new data on formation mechanism of pseudorutile globules. The endogenous genesis of mineral as a product of high-temperature oxidation of drop-liquid native intermetallic compound (Ti-Fe) from melt under reducing conditions is proved. Throughout the mantle magmatic chamber evolution involving deep gaseous fluids (H2, CH4) under conditions of oxygen deficiency the reduction regime was formed being favorable for intermetallide ore compound (Ti-Fe) segregation. Reducing conditions appeared within the melt itself and especially, in final phase melts (3-4). Under conditions of increasing facies pressure of oxygen the liquiddrop intermetallides (Ti-Fe) are subjected to high-temperature oxidation within the early magmatic stage of homogeneous pseudorutile phase with Mn, Si, Al, Ca, K impurities.