In connection with increasing flow of noble metals dispersion in river waterways at high transit speed, it seems relevant to distinguish between man-made and natural migration and determine its potential. The main aim of the study is to assess noble metals (Ru, Rh, Pd, Ag, Os, Ir, Pt, Au) migration potential of Mongol-Okhotsk gold belt in relation to oxidized and reduced forms of biogeochemical components in the Upper and Middle Amur region province. To this effect, the author has developed and tested the methods for determining the oxidized C[NMn+] forms, reduced C[NM] forms, their relations C[NMn+]/C[NM], and evaluating the natural migration potential [ E[migr]=0,059/n * lg(C[a NMn+]/ C[q NM] ]. The methods used in the study: atomic absorption, electrochemistry, photometry, catalysis and chemical analysis methods, using techniques of extraction and assay concentration in determining the mass of ordinary shares in noble metal geochemical samples with an error for the correctness, accuracy and reproducibility of [<=]30 %. The results. It is shown that the migration of noble metal on river systems with high transit speed is subjected to strong technological impact, distorting the flow of migration assessment up to 5 times. Therefore the author proposed the assessment of migration potential for thermodynamic equilibrium and established relations in the form of noble metal biogeochemical province, which is also suitable for river systems with low transit speeds. Noble metal absolute concentrations in biosphere are set by the value of standard E[Ox/Red] potentials, noble metal chemical compounds and have practically absolute interval values ??(10 ppm - 0,001 ppb). These concentrations are also equilibrium, given by thermodynamic parameters of the natural environment. Therefore, the amount of noble metal oxidized form does not depend on size of their gross concentration in landscape, but it is determined by chemical nature of the individual noble metal, radius of its mineral and physicochemical properties of biogeochemical province. For the geochemistry chain soil-water-plant-fish/animal the value of migration potential in the chain link increases. In this case: a) river transit does not uniquely describe the natural migration of noble metals, b) the ratio of oxidized and reduced forms of noble metals is a simple and reliable criterion of existing thermodynamic equilibrium of the Amur region, c) the potential of migration is negative for all noble metals of Amur biogeochemical province and shifts thermodynamic equilibrium to recovery values.